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B12 supplementation is appropriate for individuals with confirmed deficiency, vegans, older adults, those with malabsorption disorders, people who have had bariatric surgery, and those on long-term medications such as metformin or proton pump inhibitors

It thereby accelerates angiogenesis (new capillary growth) and recruits stem and progenitor cells, which aid in regenerating damaged tissues [4]

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Hypoxia in the tumor microenvironment simulates metabolic adaptation of TAMs and pro-angiogenic characteristics

Supplementary material The Supplementary material for this article can be found online at: References 1 AbeF