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Sports 25 , 315 (2015)

Collectively, these effects attenuate the infiltration of CD8 + T cells into the brain parenchyma, thereby conferring neuroprotection ( Previous studies have established that ischemic stroke induces splenic atrophy, which leads to a reduction in splenocyte counts, inhibition of T cell proliferation, and decreased secretion of inflammatory cytokines, ultimately resulting in systemic immunosuppression ( + CD8 + cytotoxic T (Tc) cells within the spleen

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J.Murillo-CabezasF.Gonzlez-MontelongoR.Ruiz de Aza-LpezZ.Rodrguez-RodrguezA.et al (2018)