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International parkinson and movement disorder society evidence-based medicine review: update on treatments for the motor symptoms of parkinsons disease

doi: 10.1371/journal.pone.0198479 116 SulahianAPorcherRBergeronATouratierSRaffouxEMenottiJet al

Mason KP, Michna E, Zurakowski D, Koka BV, Burrows PE

Furthermore, MPTP-treated mice exhibited significantly upregulated expression levels of iNOS, TNF, and IL-1 compared to controls, whereas irisin treatment notably attenuated the expression of these pro-inflammatory markers (Fig

Severe edema of the lamina propria and continuous diffuse edema of the submucosa was also evident (Figure 23A)