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Coexistence of gain-of-function JAK2 germ line mutations with JAK2V617F in polycythemia vera

doi: 10.1007/s00109-022-02185-4 42 ShenBYiXSunYBiXDuJZhangCet al

Oral administration of selenium increases GPX4 expression and inhibits cell death in T follicular helper (Tfh) cells by alleviating the generation of reactive oxygen species (ROS) 18

In animals treated chronically with naringin, mitochondrial membrane potential was reestablished, and the activity of manganese superoxide dismutasea key mitochondrial antioxidant enzyme essential for sustaining ATP productionwas significantly restored in both the hippocampus and cortex (Sachdeva et al., 2014)