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L-arginine and L-citrulline may further lower blood pressure when combined with antihypertensive medications, and they are contraindicated with prescribed nitrates due to dangerous blood pressure drops

The ESI source conditions were set as following: sheath gas flow rate of 50 arbitrary units (Arb), auxiliary gas flow rate of 15 Arb, capillary temperature of 320 C, full MS resolution of 60,000, MS/MS resolution of 15,000, collision energy of 10/30/60 in normalized collision energy (NCE) mode, and spray voltage of 3.8 kV (positive) or 3.4 kV (negative)

Entretanto, alguns pontos negativos foram observados

[DOI] [PMC free article] [PubMed] [Google Scholar] 104.Lugo-Huitrn R., Blanco-Ayala T., Ugalde-Muiz P., Carrillo-Mora P., Pedraza-Chaverr J., Silva-Adaya D., Maldonado P.D., Torres I., Pinzn E., Ortiz-Islas E., et al