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J Crohns Colitis 11, 649670

doi: 10.1016/j.jad.2008.04.013 [DOI] [PubMed] [Google Scholar] 20.Brown NC, Andreazza AC, Young LT

Darber hinaus kann durch eine verstrkte Hochregulation der Poly-(Adenosindiphosphat-Ribose)-Polymerasen-Inhibitoren (PARPi) die Apoptose und Zellproliferation moduliert werden, was eine Tumorprogression hin zu einen aggressiveren Phnotypen mit Arzneimittelresistenz und Metastasierung bedingt wird [27, 29]