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Older Adults : As you age, your bodys ability to absorb B12 decreases, making older adults more susceptible to B12 deficiency

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It can hold up to 1000 times its weight in water, making it a top ingredient for hydration

In the next, extremely unfavorable elimination step (step 2), the conjugate base of the amine is kicked out from the tetrahedral intermediate: The reaction is driven to completion in a quick, irreversible deprotonation of the carboxylic acid by the newly formed RNH