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Group 2 (DEX): Received intraperitoneal DEX (10 mg/kg) on alternate days for 28 days ( The 400 mg/kg and 800 mg/kg body weight/day doses for Spirulina platensis aqueous extract were selected based on previous studies demonstrating safety and hepatoprotective efficacy in rodent models ( Twenty-four hours after the final treatment following the 28-day study, delivery was conducted under ketamine/xylazine anaesthesia at dosages of 7.5 and 1.0 mg/kg by intraperitoneal infusion ( The liver specimens were preserved in a 10% formalin saline solution for histological analysis

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Han Z, Boyle DL, Shi Y, Green DR, Firestein GS

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