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The most important step in targeting GLN is the use of GLS to catalyze the deamination reaction of GLN to glutamate

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96 Upon activation, phosphofructokinase 1 (PFK1) can bind to the transcription factor TEAD, stabilizing its interaction with YAP/TAZ in the nucleus, promoting YAP/TAZ transcriptional output, and impacting breast cancer progression

However, the evidence of neuronal ferroptosis after TSCI in our study is still insufficient, co-localization analysis of ferroptosis indicator with neurons should be improved in future study