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The most one can say is mechanistic: raising GH and IGF-1 could, in principle, influence body composition and metabolism, and the animal models show effects on growth and body composition in a deficiency setting

Most patients describe them as quick and well-tolerated

Fatigue, cognitive dysfunction (brain fog, memory issues, attention disorder) and sleep disturbances are prominent clinical features of PASC

The Neuroprotective Potential of Metformin At the core of metformins mechanism of action is the critical disruption of the mitochondrial function