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Currently, cellular senescence is understood as the response of cells to stress induced by both endogenous and exogenous factors, such as oncogenic factors, and genotoxic stress, telomere dysfunction, or mitochondrial degradation [11]

Specifically, GHK-Cu is thought to increase the activity of antioxidant enzymes, support metal-ion homeostasis, and modulate the expression of cytokines such as TNF- and IL-6 in research models of mucosal damage

That is the signature of cumulative collagen response: no single dramatic event, just gradual improvement that compounds over time

Marrero JA, Fontana RJ, Fu S, Conjeevaram HS, Su GL, Lok AS

It helps remove toxins and free radicals from the skin