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Journal of Internal Medicine, 288 (5), 518

Environmental factors, life events, and trauma in the course of bipolar disorder

[DOI] [PMC free article] [PubMed] [Google Scholar] 95.Lee SY, Pearce EN

Microbial Cell Factories 16, 29

Maternal betaine intake (rats and pigs) can programmatically alter liver metabolism, cell proliferation, and the developmental trajectory of offspringand even the F2 generationby affecting the DNA methylation pattern of the insulin-like growth factor (IGF) gene family (IGF-1/2) in the liver of the offspring and regulating the expression of glucocorticoid receptor signaling and lipolysis genes (adipose triglyceride lipase and hormone-sensitive lipase) (25, 140145)