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GLP-1 therapy is centrally acting

Biological Science (2022)

Thiazolidinediones (TZDs), including rosiglitazone, pioglitazone and troglitazone, are applied to treat type II diabetes

The D46 residue in the DA-bound dDAT structure undergoes a 1 torsion angle shift of 100 relative to that of the NE-bound structure to interact with the primary amine of DA

Excessive nutrient intake relative to energy expenditure has fueled a dramatic increase in the incidence of diabetes 1 , which is mainly due to a relentless decline in -cell function