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Introduction Glioma is a threatening primary malignancy tumor in the central nervous system ( Recently, immunotherapy represented by PD-1/PD-L1 and CTLA-4 has shown excellent clinical effects on numerous tumors such as melanoma and non-small cell lung cancer ( The glioma immune microenvironment is composed of glioma cells, immune cells, cytokines and so on ( Ferroptosis is a form of regulated cell death driven by lipid peroxidation, a consequence of imbalance between cell metabolism and redox homeostasis ( Overview of Ferroptosis and Potential Singling Pathway in Glioma The main characteristics of ferroptosis include: cell morphology (mitochondria crista, volume reduction, and increase of membrane density)

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474,475 Consequently, rhIL-7 holds promise for maintaining T cell homeostasis, increasing T cell numbers, and enhancing their cytotoxic functions, not only in idiopathic CD4 + lymphopenia but also in the context of various cancer therapies (Table 2)

ZhangGLiZWanXZhangYZhuRLiuZet alRepression of human hepatocellular carcinoma growth by regulating Met/EGFR/VEGFR-Akt/NF-kappaB pathways with theanine and its derivative, (R)-2-(6,8-Dibromo-2-oxo-2H-chromene-3-carboxamido)-5-(ethylamino)-5-oxopentanoic ethyl ester (DTBrC)