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10.1001/archneurol.2011.235 202 HuangY.ShiX.LiZ.ShenY.ShiX.WangL.et al

In response to such irritants, AECs secrete a variety of EVs, containing components such as miR-210, miR-21 and cellular communication network factor 1 (CCN1) (40)

A scientific colleague and friend once quipped, if you don't have a mechanism just say it is ROS. Unfortunately, there is some truth to this statement