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No comprehensive metabolism study in humans has been published

J Clin Oncol 23(27):67196729 Kulagina N, Besseau S, Godon C, Goldman GH, Papon N, Courdavault V (2021) Yeasts as biopharmaceutical production platforms

Teleosts also present an interesting great feature that can serve as an advantage against the rodent models: the possibility to regenerate the brain tissue (Kizil et al., 2012

Therapeutic intervention with senolytics, such as dasatinib and quercetin, can eliminate these senescent cells, restoring plaque compaction and reducing neurotoxicity, thereby underscoring the necessity of autophagy for maintaining the protective DAM identity [108]