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With respect to the rejection index, it must be noted that the summation of sighs and apneas under non-eupneic breathing under the rejection index is obviously simplistic and does not do justice to the different mechanisms that elicit these individual respiratory patterns

J Neurosci Res 14:207215 Marosi K, Kim SW, Moehl K, Scheibye-Knudsen M, Cheng A, Cutler R, Camandola S, Mattson MP (2016) 3-Hydroxybutyrate regulates energy metabolism and induces BDNF expression in cerebral cortical neurons