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The Nobel chronicles

Baroni L, Goggi S, Battaglino R et al

236 Furthermore, glucose starvation leads to a suppressed lactate/pyruvate cycle, which inhibits neovascularization, hypoxia-induced vascular epidermal growth factor activation, and angiogenesis, and causes ultimate necrosis in tumor cells, especially for colon adenocarcinoma xenografts

Nonathletes often conceive of performance enhancers as the lazy option, but its typically the opposite: athletes take them so they can train even more