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In vitro experiments demonstrated that N4Py-S-S-FA elicited good selectivity toward FR-expressing KB and IGROV-1 tumor cells and is similarly cytotoxic as the parent iron complex of the ligand N4Py

10.1016/j.bbrc.2019.06.033 Biochem

It was removed from the FDA's Category 2 restricted list on April 22, 2026, but that alone doesn't authorize compounding pharmacies to prepare it for human use

doi: 10.3390/ijms21144908 23 CarafoliE.KrebsJ

Brus B, Koak U, Turk S, Pilar A, Coquelle N, Kos J, Stojan J, Colletier J-P, Gobec S (2014) Discovery, biological evaluation, and crystal structure of a novel nanomolar selective butyrylcholinesterase inhibitor