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[3] That reversibility is a crucial, often-omitted caveat: tesamorelins effect is a maintained pharmacological state, not a one-time fix. We discuss the visceral-fat data and its limits further in our reference on tesamorelins visceral-fat effects and safety profile

4.6 Absence of dynamic prediction windows Given that the onset of high-altitude illnesses unfolds as a continuous process, whereas current prediction models predominantly rely on static data, capturing dynamic changes and translating them into real-time precise predictions remains a key challenge yet to be overcome