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Description

Eye Res 74 , 245254

This protocol delivers maximum copper peptide exposure but requires skin that tolerates high active ingredient loads

Not much information about their formation in humans is available but a study showing the metabolism of pivalic acid (a component of Pivaloyloxyethyl, a prodrug of methyldopa) via the acyl CoA formation pathway and not by glucuronidation, as seen in rats, monkeys and rabbits, suggests that humans might be particularly susceptible (120)