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FACTORS CONTRIBUTING TO AD Key Molecules Involved in AD Pathogenesis The contributing factors to AD involve both genetic and non-genetic components

NAC is commonly used in respiratory-support formulas because it can help support mucus clearance

IGFBP-5 can be either stimulatory or inhibitory depending on context and binds to extracellular matrix, creating localized IGF reservoirs relevant to bone and muscle

Z., & Ranjan, O

In addition, ferroptosis is orchestrated by a variety of cellular metabolic pathways, including redox homeostasis, iron metabolism, mitochondrial activity, amino acid and lipid and sugar metabolism, and various signaling pathways [7, 10]