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Name: lippincot wolter klower Wolters Kluwer Lippincott Manual of Nursing Practice - Lippincott Nursing Practice Manual, 11 Edition wolterskluwerhealth #nursingeducation #ai #lippincott #innovationineducation
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10.1093/oxfordjournals.humrep.a138480 27

PMID: 22084174

Importantly, HER-2/neu overexpression is a clinically relevant target in human breast cancers, making this model highly translational for cancer risk mitigation in susceptible populations

Kassim M, Achoui M, Mustafa MR, Mohd MA, Yusoff KM, et al

For homologous recombination mediated BAC deletions, ~1-kilo-base pair (kb) sized 5 and 3 arms were amplified via polymerase chain reaction (PCR) and cloned into the pGEM - T - easy vector (Promega) and in between these arms, an Ampicillin (Amp)-resistant (r) gene cassette or a Kanamycin (Kan)-r cassette put between two FRT sites was subcloned