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Cells have developed multiple mechanisms to decrease the flux through glycolysis, thereby increasing glucose 6-phosphate levels

Reactive oxygen species (ROS) and reactive nitrogen species (RNS) are types of FR produced in aerobic cells, playing a role in aging and age-related diseases [14]

Supported by these data, novel therapeutic approaches for LRRK2-associated PD, as well as idiopathic PD, have focused on the development and use of LRRK2 kinase inhibitors (Fig

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