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Current strategies can be broadly categorized into three approaches: (1) direct inhibition of HMGB1 to block its release or signaling via TLR4/RAGE

Mechanistic target of rapamycin activation triggers IL-4 production and necrotic death of double-negative T cells in patients with systemic lupus erythematosus

The commentary accompanying the original paper highlighted these results as evidence that senescent cell elimination could produce systemic rejuvenation rather than isolated organ-specific improvements (Krimpenfort & Berns, 2017)

Compared with the model group, DHI increased the expression of SOD, GSH, and SATB1 and decreased the expression of MDA, TfR1, and TF ( Danlou tablet (DLT) is composed of Pericarpium Trichosanthis , Allium macrostemon Bunge, Puerariae Lobatae Radix , L