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6 The stability of the model results has also been demonstrated by both types of sensitivity analysis performed, suggesting that these findings are likely to be applicable to other health-care settings and systems outside Italyprovided that there are no major differences in the ICU patient population, and/or the organisation and costs of the ICU or more generally in tertiary care

The structure of the molecule is recognisable by its glutamic acid, cysteine and glycine residues (Fig

244 As of mid-2025, the WatchPAT 300 and the WatchPAT ONE are the latest models (both launched in 2019)

Megaloblastic anemia due to B12 deficiency is either caused by inadequate intake, in which case oral supplementation is sufficient, or poor absorption potentially due to a reduction in intrinsic factor. Intrinsic factor, which is synthesized by cells in the stomach, is secreted into the gastrointestinal tract to bind dietary B12 and facilitate its absorption (Wickramasinghe 2006)

and W.M