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(155) found that a molecular driver of early onset IBD, specifically CD, is the recessive inheritance of NOD2 alleles, most likely a consequence of impaired NOD2 protein activity

We observed a significant decrease in MMP-2 activity and a significant increase in MMP-9 activity in GGC-treated cells, suggestive of the differential effect of GGC and increased GSH on MMPs

Of note, the preferred sequence for MPP8 chromo, KAKKTGK, mapped to Calcium permeable stress-gated cation channel 1 (CSC1) in the human proteome

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