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Description

These biological clocks operate autonomously within the cells of different tissues, maintaining a dynamic balance that supports daily physiological functions (Fagiani et al., 2022)

Ruangrai W, Jindadamrongwech S

doi: 10.1038/s41571-018-0003-5

They are a new category of medicine

It illustrates that electron-donating groups of TPM-NMe could enhance the electron density at the central position of the molecular skeleton (as shown by the electrostatic potential map with red color), which simultaneously stabilizes the excited-state geometry and strengthens TSC, resulting in redshifted wavelength (from 420 nm to 447 nm) and increased efficiency (from 2.7% to 6.9%) compared to TPM