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CAFs and tumor cells secrete factors such as TGF- and CXCL12, which suppress T-cell effector function and sequester T cells within the stromal compartment [155, 156]

Front Immunol (2022) 13:955069

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All work with infectious DENV was performed in a biosafety level 3 (BSL3) laboratory according to the safety guidelines of the Department of Molecular Medicine (University of Padua, Italy) committee on microbiological safety