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This latter finding is particularly important given the possibility that cerebral hypoperfusion may act as a precursor to the development of mild cognitive impairment (MCI), a condition that often precedes the onset of AD [46]

Appl Environ Microbiol 2007

[DOI] [PMC free article] [PubMed] [Google Scholar] 220.Teng CL, Yang VC

In native biological models, complex structural injuries and chronic inflammatory states engage multiple, overlapping cellular networks

Also, The National Institutes of Health and the Institute of Medicine have determined that no adverse effects have been established from excess amounts of B-12 in the body