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The dense capsule surrounding the enlarging prostate prevents it from further expansion outward, which in turn forces the prostate to press against the urethra, and partially block urine flow (Figure 2)

Finally, mRNA expressions of the proteins involved in SOCE, i.e., STIM and Orai, were measured

This analysis of AD through network pharmacology provides a promising roadmap for addressing the diseases multifaceted pathology, paving the way for innovative, multi-targeted therapeutic solutions (Figure 2)

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326,327 While ChREBP deficiency improves IR and hepatic steatosis by inhibiting the entire lipogenic and esterification process