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Description

Superinhibition of sarcoplasmic reticulum function by phospholamban induces cardiac contractile failure

Epub 2018 Feb 27 7

Vergely, C

This in vitro potency translated into in vivo efficacy, where a single dose of the BsADC (5 mg/kg) achieved 85% tumor growth inhibition in a BT-474 xenograft model, compared to 45% inhibition by the conventional ADC at the same dose