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S.DarleyR

Glutathin (Mochida)

This reprogramming is coordinated by dysregulation of key metabolic enzymes, including hypoxia-inducible factor 1 (HIF-1)-induced HK2, phosphofructokinase-2/fructose-2,6-bisphosphatase 3 (PFKFB3), pyruvatebkinase M2 (PKM2), and lactate dehydrogenase (LDHA), as well as increased glucose transporter 1 (GLUT1) (16, 17)