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The new research, which was conducted with Schistosoma maintained in laboratory conditions, shows that an oxadiazole compound was effective in inhibiting a crucial worm enzyme, called thioredoxin glutathione reductase (TGR)

Quercetin: A novel inhibitors of Ca2+ influx and exocytosis in rat peritoneal mast cells

KYNA can confer protection against excitotoxicity via glutamatergic antagonism, yet excessive levels may simultaneously impair cholinergic signalling through 7nAChRs, contributing to mood and cognitive dysfunction

In addition, with the growing insights into the production and utilization of one-carbon units in cancer cells, multiple therapeutic strategies have been proposed, including nutrient therapy and targeting enzymes in one-carbon metabolism pathways

Gorovits, R