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doi: 10.1056/nejm199703273361303 248 KelleniMT

Key potential benefits: Reduction of visceral abdominal fat Particularly useful in patients with stubborn central fat that is resistant to diet and exercise Metabolic and cardiovascular support May help improve lipid profiles Potentially beneficial for cardiometabolic health Possible cognitive benefits Emerging data suggest improved cognitive function in some populations, which can be especially relevant for aging patients By enhancing endogenous GH release rather than providing direct GH, Tesamorelin offers a targeted way to influence fat distribution and metabolic health

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Costs and access Peptide therapy is typically not covered by insurance: PT-141 (Vyleesi) may be covered for HSDD with prior authorization Most other peptides are considered "off-label" or not FDA-approved for specific uses Compounding pharmacy costs vary widely Expect to pay out-of-pocket for most peptide therapies Monthly costs range from $100-500+ depending on the peptides used