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Selenoprotein polymorphisms are a risk factor for the development of systolic heart failure (HF) and peripheral atherosclerosis but prevent the development of abdominal aortic aneurysm (AAA)

Inhibition of glutaminase preferentially slows growth of glioma cells with mutant IDH1

Although the same enzymatic activities participate in the GSH-pathway in both fungal species, the comparison between S.bacillaris strains revealed a high number of SNPs able to impact the functioning of twenty genes (Table 1)

When methyl groups are transferred from SAMe, S-adenosylhomocysteine is formed

Metabolic processes trigger different types of ROS, that are able to, if present at inadequate levels, oxidize DNA and induce various damage, such as double-stranded DNA breaks and deficiencies, often found in human tumors (De Bont and van Larebeke, 2004)