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We explore how close researchers may be to a cure, including promising gene therapy clinical trials, and what experts say still needs long-term study.

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B12 injections commonly cause mild injection site reactions and rarely hypersensitivity or hypokalaemia

Children's requirements are lower and increase with age: infants aged 0-6 months have a safe intake of about 0.3 g daily, those aged 712 months need 0.4 g daily, children aged 13 years require 0.5 g, those aged 46 years need 0.8 g, and children aged 710 years should receive 1.0 g daily

Nishiyama M, Hong K, Mikoshiba K, Poo MM, Kato K (2000)