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Glutamate both in neurons and glial cells is synthesized through the tricarboxylic acid cycle and additionally in neurons by the glutamateglutamine cycle, where it is accumulated in vesicles for future release

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De rol van glutathion is dus om de lichaamscellen te beschermen tegen de schadelijke effecten van verschillende soorten gifstoffen - van die uit de externe omgeving, zoals luchtverontreinigende stoffen of chemicalin, tot die welke intern worden geproduceerd, zoals producten van het metabolisme