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The production of this transporter can be increased through exercise [8]

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Despite all this evidence suggesting that disruption of protein homeostasis may impair interneuronal communication, the specific mechanisms linking ATXN3 to these effects remain to be investigated

0.5 mg/0.1 ml saline/each eye) in rats immediately produced moderate generalized irregularity in the diameter of blood vessels with moderate atrophy of the optic disc and faint presentation of the choroidal blood vessels, and these lesions rapidly progressed to the severe stage