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Among them, branched ubiquitin chains, in which one ubiquitin moiety is modified with two or more ubiquitin molecules through different linkages, function as a priority signal for proteasome-mediated protein degradation 3,4

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N-Acetyl Epithalon Amidate represents a structurally modified form of this parent compound, incorporating N-terminal acetylation and C-terminal amidation two well-characterized peptide chemistry modifications designed to address the inherent instability of short-chain peptides in biological matrices

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