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The deprivation of the SGOC metabolic pathway can lead to a significant drop in total ATP levels in rapidly proliferating cells, thus reducing the transfer of methyl to DNA and RNA, which can lead to changes in methyl transfer but will not induce the activation of AMP activated protein kinase (AMPK) [48]

Methodology: We developed and validated an HPLC-UV method for precision, accuracy, linearity, limits of detection (LOQ), and limits of quantitation (LOQ) for the quantitative analysis of both GSH and four associated impurities A-D