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M2 KCs inhibit NK cell activation either through direct cell-to-cell contact or indirectly via cytokines, which subsequently promotes hepatocyte mitosis after PHx

Furthermore, oridonin increased the expression of the pregnane X receptor, thereby upregulating CYP3A4 and P-glycoproteinkey elements in detoxification and mucosal barrier maintenance, thus offering a dual anti-inflammatory and barrier-protective effect

GLP-1 suppresses feeding behaviors and modulates neuronal electrophysiological properties in multiple brain regions

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Detoxification: Elimination of toxins and waste products, liver cell cleansing from antibiotic and alcohol effects