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In vascular biology, the peptide seems to modulate nitric oxide synthesis, driving angiogenesis by upregulating eNOS and subsequent NO production

doi: 10.3945/ajcn.111.027995

On the following day, samples were changed into fresh culture media containing peroxynitrite (Cayman, 81565) alone for 24 or 48 h, or with the following drugs for 48 h as indicated in the text: ebselen (30 M, Sigma-Aldrich, E3520)