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In the kidneys, urinary BHB is reabsorbed in the proximal tubules through sodium-coupled monocarboxylate transporters 1 (SMCT1) and 2 (SMCT2)

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From solution NMR studies of BP lesions within B-DNA 57 , the 10 S (+)- trans -adducts and 10 R ()- trans -adducts reside in the minor groove, while the 10 R (+)- cis -adducts and 10 S ()- cis -adducts adopt an intercalative conformation where the pyrenyl ring system displaces the dG:dC base pair and assumes an intercalated conformation 44, 45

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The photo-oxidation resistance of the neat PLA and PLA/PA11 blend is significantly reduced due to the presence of both metal oxides, and this must be considered when designing potential applications