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Glycine supports insulin sensitivity through complementary mechanisms

Interim phase 1 data in heavily pretreated mCRC showed 28% ORR and 94% DCR across prioritized dose levels, 43% ORR at 10 mg/kg, and median PFS 5.8 months

doi: 10.3389/fmicb.2025.1688325 Received 19 August 2025 Accepted 23 October 2025 Published 11 November 2025 Volume 16 - 2025 Edited by Laura Mitrea, University of Agricultural Sciences and Veterinary Medicine of Cluj-Napoca, Romania Reviewed by Chen Ye, Tongji University, China Wu Yuqi, Microbiota I-Center Limited, Hong Kong SAR, China Updates Copyright 2025 Feng, Wang, Si, Lu, Lu, Gao, Yang, Wu, He and Wu

While complete elimination of mature stretch marks is unlikely with any non-surgical treatment, GHK-Cu can visibly improve their appearance and texture over several cycles, particularly when combined with consistent topical application to the affected areas

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