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Durable remissions with Ivosidenib in IDH1-mutated relapsed or refractory AML

Uncontrolled high blood sugar induces oxidative stress, which is accompanied by an increase in inflammatory cytokines (proteins) and advanced glycation end products (glycotoxins)

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It reduces more complex lipids such as phosphatidylcholine hydroperoxides, fatty acid hydroperoxides, and cholesterol [26]

In fact, GSH is ubiquitous across all kingdoms of life and serves in a vast array of cellular processes