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Severe allergic reactions affect less than 2% of users but include facial swelling, hives, difficulty breathing, and intense burning that doesn't improve after 48 hours

Since gold ions are toxic to the NP producing cell, the reduction to AuNPs is desirable, however the stress to the cell and its inhibitory effect have to be investigated

108 Furthermore, NGF loaded in transferrin- and cereport-functionalized liposomes enhanced the permeability across the BBB

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Notably, DRP-104 demonstrates the ability to counter T cell exhaustion and enhance the functionality of both CD4 + and CD8 + T cells [188]