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Alikhan, A., Felsten, L

Six years ago, the concept of GLP-1s was so foreign to everybody until there were large clinical trials with them, and now theyre everywhere. Still, some physicians embrace the modality despite the lack of human studies

Completing the picture is the role of the gut microbiota, which comprises vast ecosystems composed of an exorbitant number of microbes, including viruses, fungi and bacteria

Previous works have found that M1 and M2 macrophages show distinct metabolite profiles such as fatty acid utilization, OxPhos, and glycolysis (Fuchs et al