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This is the first time in Medicare history that CMS has set two separate conversion factors

Oncogene 27 , 69306938 (2008)

Two small randomized, double-blind, placebo-controlled study found that once-daily oral L-histidine consumption for 4 to 12 weeks improved eczema scores (SCORAD) by ~34-39% in adults in 4 weeks and 49% in kids in 12 weeks, while placebo did not