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[DOI] [PMC free article] [PubMed] [Google Scholar] 69.Crujeiras A.B., Izquierdo A.G., Primo D., Milagro F.I., Sajoux I., Jacome A., Fernandez-Quintela A., Portillo M.P., Martinez J.A., Martinez-Olmos M.A., et al

What is the main takeaway from this comparison

This can be achieved by engineering two pools of T cells, each expressing different CARs, or by incorporating multiple antigen recognition domains within a single CAR construct, called a compound CAR (cCAR) (46)

doi: 10.1006/niox.2001.0419

We found that co-application of clofazimine and remdesivir affects SARS-CoV-2 replication in a manner that extends beyond the additive activity predicted by the Bliss independence model (maximal Bliss synergy score of 44.28), which indicates that these two drugs operate in a synergistic antiviral relationship (Extended Data Fig